CAB39
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Official Full Name
calcium binding protein 39 -
Overview
Together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of STK11. -
Synonyms
CAB39;calcium binding protein 39;calcium-binding protein 39;CGI 66;MO25;MO25alpha;CGI-66;FLJ22682
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- E.coli
- Sf9 Insect Cell
- Mammalian Cell
- Human
- HEK293
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CAB39 involved in several pathways and played different roles in them. We selected most pathways CAB39 participated on our site, such as mTOR signaling pathway,AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAB39 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mTOR signaling pathway | AKT1S1,PIK3R5,RPS6KA6,PDPK1,EIF4E1C,AKT3A,RPS6KA3,TSC2,RPS6KA1,RPS6KB1B |
| AMPK signaling pathway | RAB11B,ADRa1A,G6PC,CPT1B,PRKAG3,ACACA,INS2,RHEB,PFKP,FBP1 |
Protein Function
CAB39 has several biochemical functions, for example, kinase binding,protein binding,protein kinase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAB39 itself. We selected most functions CAB39 had, and list some proteins which have the same functions with CAB39. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein serine/threonine kinase activator activity | MAP2K1,IGF2,PARP16,MAP2K2,FAM20A,CALM1,SPRY2,STK4,CALM3,ALS2 |
| protein binding | RAP2B,FSHB,MCEE,ATG4A,TOM1L1,EIF3H,FBN1,RARG,B9D2,IRS4 |
| protein kinase activator activity | MT3,NCKAP1L,DBF4B,PIK3CA,STK11,TOM1L1,FAM58A,STRADA,GPRC5B,WNT11 |
| kinase binding | TAX1BP1,PRPSAP1,BARD1,FAS,UBQLN1,STRADA,HSP90AB1,PRKAA1,STUB1,TNFAIP3 |
Interacting Protein
CAB39 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAB39 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAB39.
STK11;STRADB;STK26
CAB39 Related Signal Pathway
Resources
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References
- Afroze, T; Yang, G; et al. Calcium Efflux Activity of Plasma Membrane Ca2+ ATPase-4 (PMCA4) Mediates Cell Cycle Progression in Vascular Smooth Muscle Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 289:7221-7231(2014).
- Wittkowski, H; Kuemmerle-Deschner, JB; et al. MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes. ANNALS OF THE RHEUMATIC DISEASES 70:2075-2081(2011).
