Recombinant Human Calcium Binding Protein 39, GST-tagged

• Cat.No.: CAB39-1471H
• Product Overview: Recombinant full-length human MO25alpha was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 63kDa.

Specification

• Cat. No.: CAB39-1471H
• Description: MO25α (mouse protein 25 alpha) is a 40-kDa protein that interacts with the STE20-related adaptor-alpha (STRADα) pseudo kinase to form a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. LKB1 plays a critical role in cell proliferation, polarity and energy metabolism. LKB1 is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). MO25α binds directly to a conserved Trp-Glu-Phe sequence at the STRADα C terminus, and markedly enhances the binding of STRADα to LKB1 thereby increasing LKB1.
• Source: Sf9 insect cells using baculovirus.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CAB39 calcium binding protein 39 [ Homo sapiens ]
• Synonyms: CAB39; calcium binding protein 39; MO25; CGI-66; FLJ22682; Protein Mo25
• Gene ID: 51719
• mRNA Refseq: NM_001130849
• Protein Refseq: NP_001124321
• MIM: 612174
• UniProt ID: Q9Y376
• Chromosome Location: 2q37.1
• Pathway: mTOR signaling pathway; Integration of energy metabolism
• Function: protein binding