Recombinant Human C6, GST-tagged

• Cat.No.: C6-10553H
• Product Overview: Recombinant Human C6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 586-934a.a.
• Description: This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: C6 complement component 6 [ Homo sapiens ]
• Official Symbol: C6
• Synonyms: C6; complement component 6; complement component C6
• Gene ID: 729
• mRNA Refseq: NM_000065
• Protein Refseq: NP_000056
• MIM: 217050
• UniProt ID: P13671
• Chromosome Location: 5
• Pathway: Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: protein binding