Recombinant Human C5AR1 Protein, His-tagged

• Cat.No.: C5AR1-01H
• Product Overview: Recombinant protein from the full-length sequence of Homo sapiens complement C5a receptor 1 (C5AR1) (NM_001736), with a His tag was expressed in Human Cells.

Specification

• Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
• Source: Human Cells
• Species: Human
• Tag: His
• Molecular Mass: 39.1 kDa
• Endotoxin: < 0.1 ng/μg of protein (<1EU/μg)
• Purity: > 90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Gene Information

• Gene Name: C5AR1 complement C5a receptor 1 [ Homo sapiens (human) ]
• Official Symbol: C5AR1
• Synonyms: C5AR1; complement C5a receptor 1; C5A; C5AR; C5R1; CD88; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a-R; complement component 5a receptor 1
• Gene ID: 728
• mRNA Refseq: NM_001736
• Protein Refseq: NP_001727
• MIM: 113995
• UniProt ID: P21730