Recombinant Human C19ORF2

Cat.No. : C19ORF2-27164TH
Product Overview : Recombinant full length human C19orf2 with proprietary tag; amino acids 1-535, approximately 86kDa.
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Species : Human
Source : E.coli
Tag : Non
Protein Length : 1-535 a.a.
Description : The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Full Length : Full L.
Gene Name C19orf2 chromosome 19 open reading frame 2 [ Homo sapiens ]
Official Symbol C19ORF2
Synonyms C19ORF2; chromosome 19 open reading frame 2; unconventional prefoldin RPB5 interactor; FLJ10575; NNX3; PPP1R19; protein phosphatase 1; regulatory subunit 19; RMP; RPB5 mediating protein; URI;
Gene ID 8725
mRNA Refseq NM_134447
Protein Refseq NP_604431
MIM 603494
Uniprot ID O94763
Chromosome Location 19q12
Function protein binding; transcription corepressor activity; unfolded protein binding;

Not For Human Consumption!

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