Recombinant Human C14orf129, His-tagged

• Cat.No.: C14orf129
• Product Overview: Recombinant human C14orf129 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Cat. No.: C14orf129-3504H
• Description: C14orf129 (GSK3 β interaction protein) is defined as a naturally occurring protein that is homologous with the GSK3beta interaction domain of Axin and is able to negatively regulate GSK3beta of the Wnt signaling pathway. C14orf129 may affect GSK3β activity on neurite outgrowth by inhibiting the specific phosphorylation of tau (ser396).
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50mM NaCl
• Molecular Weight: 17.8kDa (159aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH METDCNPMEL SSMSGFEEGS ELNGFEGTDM KDMRLEAEAV VNDVLFAVNN MFVSKSLRCA DDVAYINVET KERNRYCLEL TEAGLKVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKRDGQS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: C14orf129 chromosome 14 open reading frame 129 [ Homo sapiens ]
• Synonyms: chromosome 14 open reading frame 129; GSKIP; HSPC210; MGC4945; C14orf129; GSK3-beta interaction protein; GSK3beta interaction protein
• Gene ID: 51527
• mRNA Refseq: NM_016472
• Protein Refseq: NP_057556
• UniProt ID: Q9P0R6
• Chromosome Location: 14q32.2
• Function: protein binding