Recombinant Human BTD, MYC/DDK-tagged

• Cat.No.: BTD-8393H
• Product Overview: Recombinant Human BTD fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.

Specification

• Description: The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 56.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: BTD biotinidase [ Homo sapiens (human) ]
• Official Symbol: BTD
• Synonyms: BTD; biotinidase; biotinase; NP_000051.1; NP_001268652.1; NP_001268653.1; NP_001268654.1; NP_001268655.1; EC 3.5.1.12
• Gene ID: 686
• mRNA Refseq: NM_000060
• Protein Refseq: NP_000051
• MIM: 609019
• UniProt ID: P43251
• Chromosome Location: 3p25
• Pathway: Defects in vitamin and cofactor metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors
• Function: biotin carboxylase activity; biotinidase activity