Recombinant Human BST2, His-tagged

• Cat.No.: BST2-3569H
• Product Overview: Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (50-161aa).

Specification

• Cat. No.: BST2-3569H
• Description: BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
• Molecular Mass: 14.8 kDa (133aa), confirmed by MALDI-TOF
• Purity: > 80 % by SDS-PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay )
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: BST2 bone marrow stromal cell antigen 2 [ Homo sapiens ]
• Official Symbol: BST2
• Synonyms: BST2; bone marrow stromal cell antigen 2; NPC-A-7; CD317; TETHERIN; HM1.24 antigen; bone marrow stromal antigen 2; BST-2; Tetherin; tetherin; CD317 antigen; Bone marrow stromal cell antigen 2
• Gene ID: 684
• mRNA Refseq: NM_004335
• Protein Refseq: NP_004326
• MIM: 600534
• UniProt ID: Q10589
• Chromosome Location: 19p13.1
• Function: protein homodimerization activity; signal transducer activity