Recombinant Human BRMS1, GST-tagged

• Cat.No.: BRMS1-10293H
• Product Overview: Recombinant Human BRMS1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-246a.a.
• Description: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: BRMS1 breast cancer metastasis suppressor 1 [ Homo sapiens ]
• Official Symbol: BRMS1
• Synonyms: BRMS1; breast cancer metastasis suppressor 1; breast cancer metastasis-suppressor 1; DKFZP564A063; DKFZp564A063
• Gene ID: 25855
• mRNA Refseq: NM_001024957
• Protein Refseq: NP_001020128
• MIM: 606259
• UniProt ID: Q9HCU9
• Chromosome Location: 11q13-q13.2
• Function: NF-kappaB binding; protein binding