Recombinant Human BRD4, His-tagged

• Cat.No.: BRD4-1921H
• Product Overview: Recombinant protein includes Bromo 2 domain (49-170 aa) with an N-terminal His-tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 49-170 aa
• Description: BrD4 protein is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. It plays a role in a process governing chromosomal dynamics during mitosis.
• Appearance: Liquid
• Form: rh-BrD4 is supplied as a solution in 50mM Tris, pH 8.0, 150 mM NaCl and 10% glycerol.
• Molecular Mass: 14.6kDa (113aa, 49-170aa)
• Purity: ≥98% by SDS-PAGE
• Usage: For Research Use Only! Not For Use in Humans.
• Storage: Stable for 1 year at –80°C. Avoid multiple freeze/thaw cycles as activity may decrease.

Gene Information

• Gene Name: BRD4 bromodomain containing 4 [ Homo sapiens (human) ]
• Official Symbol: BRD4
• Synonyms: BRD4; bromodomain containing 4; CAP; MCAP; HUNK1; HUNKI; bromodomain-containing protein 4; bromodomain-containing 4; chromosome-associated protein; EC 3.1.1.31
• Gene ID: 23476
• mRNA Refseq: NM_014299
• Protein Refseq: NP_055114
• MIM: 608749
• UniProt ID: O60885
• Chromosome Location: 19p13.1
• Function: DNA binding; protein binding