Recombinant Human BRD2 cell lysate

• Cat.No.: BRD2-177HCL

Specification

• Description: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: BRD2 bromodomain containing 2 [ Homo sapiens ]
• Official Symbol: BRD2
• Synonyms: BRD2; bromodomain containing 2; bromodomain-containing protein 2; D6S113E; FSRG1; KIAA9001; NAT; RING3; O27.1.1; bromodomain-containing 2; really interesting new gene 3 protein; female sterile homeotic-related gene 1; FSH; RNF3; FLJ31942; DKFZp686N0336
• Gene ID: 6046
• mRNA Refseq: NM_001113182
• Protein Refseq: NP_001106653
• MIM: 601540
• UniProt ID: P25440
• Chromosome Location: 6p21.3
• Pathway: Regulation of retinoblastoma protein, organism-specific biosystem
• Function: protein serine/threonine kinase activity