Recombinant Human Bone Morphogenetic Protein 3

• Cat.No.: BMP3-40H
• Product Overview: Recombinant human BMP3 is a 31.6 kDa homodimeric protein consisting of two 134 amino acid polypeptide chains.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues.
• Biological Activity: Testing is in progress.
• Molecular Weight: 31.6 kDa
• Form: Lyophilized without additives.
• Appearance: Lyophilized protein
• Endotoxin Level: <0.1 ng/μg
• Reconstitution: Centrifuge the vial prior to opening. Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
• Purity: >98% by SDS-PAGE and HPLC analyses
• Storage: The lyophilized protein is best-stored desiccated below 0°C. Reconstituted BMP-5 should be stored in working aliquots at -20°C.
• Pathways: Adipogenesis

Gene Information

• Gene Name: BMP3 bone morphogenetic protein 3 [ Homo sapiens ]
• Official Symbol: BMP3
• Synonyms: BMP3; bone morphogenetic protein 3; BMP-3A; bone morphogenetic protein 3; BMP-3; osteogenin; OTTHUMP00000160802; bone morphogenetic protein-3; bone morphogenetic protein 3A; bone morphogenetic protein 3 (osteogenic)
• Gene ID: 651
• mRNA Refseq: NM_001201
• Protein Refseq: NP_001192
• MIM: 112263
• UniProt ID: P12645
• Chromosome Location: 4q21
• Function: BMP receptor binding; cytokine activity; growth factor activity; receptor binding