Recombinant Human BMX, GST-tagged, Active

• Cat.No.: BMX-251H
• Product Overview: Recombinant full-length human BMX was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW = 110 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX, is found to induce activation of the Stat signaling pathway.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: BMX BMX non-receptor tyrosine kinase [ Homo sapiens ]
• Synonyms: BMX non-receptor tyrosine kinase; ETK; PSCTK2; PSCTK3; BMX; OTTHUMP00000022965; NTK38 tyrosine kinase; Etk/Bmx cytosolic tyrosine kinase; cytoplasmic tyrosine-protein kinase BMX; EC 2.7.10.2; NTK38; OTTHUMP00000022964; OTTHUMP00000022966; Epithelial and endothelial tyrosine kinase; Bone marrow tyrosine kinase gene in chromosome X protein
• Gene ID: 660
• mRNA Refseq: NM_001721
• Protein Refseq: NP_001712
• MIM: 300101
• UniProt ID: P51813
• Chromosome Location: Xp22.2
• Pathway: Apoptosis
• Function: non-membrane spanning protein tyrosine kinase activity; ATP binding; metal ion binding; nucleotide binding; protein binding; signal transducer activity; transferase activity; zinc ion binding