Recombinant Human BMP2

• Cat.No.: BMP2-26315TH
• Product Overview: Recombinant Human BMP2. A 26 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 283-396 aa
• Description: The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation.
• Tissue specificity: Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
• Form: Lyophilised:Centrifuge the vial prior to opening.Reconstitute in water containing BSA (50ug of BSA per 1ug of protein) to a concentration of 0.1-1.0 mg/ml.This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C f
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg).
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
• Sequence Similarities: Belongs to the TGF-beta family.

Gene Information

• Gene Name: BMP2 bone morphogenetic protein 2 [ Homo sapiens ]
• Official Symbol: BMP2
• Synonyms: BMP2; bone morphogenetic protein 2; BMP2A
• Gene ID: 650
• mRNA Refseq: NM_001200
• Protein Refseq: NP_001191
• MIM: 112261
• Uniprot ID: P12643
• Chromosome Location: 20p12
• Pathway: Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: BMP receptor binding; SMAD binding; activin receptor activity, type II; cytokine activity; growth factor activity