Recombinant Human BMI1, GST-tagged

• Cat.No.: BMI1-27487H

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• ProductOverview: Recombinant Human BMI1 protein, fused with a GST tag, was expressed in E. coil.
• Description: BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1 gene.
• Purity: 95.0%
• Sequenceof amino acids: MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLF KNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAA MTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELE
• Formulation: Liquid in 6M guanidine hydrochloride,20mM Tris
• Applications: SDS-PAGE, ELISA, Western blot
• Storage: Store at 2-8°C for immediate use or -20°C for long term storage, avoid repeat freeze thaws.

Gene Information

• Gene Name: BMI1 BMI1 polycomb ring finger oncogene [ Homo sapiens ]
• Synonyms: BMI1; BMI1 polycomb ring finger oncogene; PCGF4; RNF51; FLVI2/BMI1; MGC12685; polycomb complex protein BMI-1; polycomb complex protein BMI-1; flvi-2/bmi-1; ring finger protein 51; polycomb group protein Bmi1; polycomb group RING finger protein 4; B lymphoma Mo-MLV insertion region 1 homolog; murine leukemia viral (bmi-1) oncogene homolog
• Gene ID: 648
• mRNA Refseq: NM_005180
• Protein Refseq: NP_005171
• MIM: 164831
• UniProt ID: P35226
• Chromosome Location: 10p11.23
• Pathway: Senescence and Autophagy; Transcriptional misregulation in cancer; Validated targets of C-MYC transcriptional activation
• Function: RING-like zinc finger domain binding; chromatin binding; protein binding; sequence-specific DNA binding; ubiquitin-protein ligase activity; zinc ion binding