Recombinant Human BIRC2 protein, His/GST-tagged

• Cat.No.: BIRC2-5894H
• Product Overview: Recombinant Human BIRC2(1-221aa) fused with His/GST tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: 1-221 a.a.
• Description: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis.
• Form: Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
• Molecular Mass: 60.2 kDa
• Purity: Greater than 95%
• Storage: Store at +4 centigrade for up to 1 month, or aliquot and store at -80 centigrade for up to 12 months. Avoid repeat freeze-thaw cycles.

Gene Information

• Gene Name: BIRC2 baculoviral IAP repeat containing 2 [ Homo sapiens ]
• Official Symbol: BIRC2
• Synonyms: BIRC2; baculoviral IAP repeat containing 2; API1, baculoviral IAP repeat containing 2; baculoviral IAP repeat-containing protein 2; apoptosis inhibitor 1; c IAP1; cIAP1; hiap 2; MIHB; NFR2 TRAF signalling complex protein; RNF48; IAP-2; IAP homolog B; RING finger protein 48; inhibitor of apoptosis protein 2; baculoviral IAP repeat-containing 2; NFR2-TRAF signalling complex protein; TNFR2-TRAF-signaling complex protein 2; API1; HIAP2; Hiap-2; c-IAP1
• Gene ID: 329
• mRNA Refseq: NM_001166
• Protein Refseq: NP_001157
• MIM: 601712
• UniProt ID: Q13490
• Chromosome Location: 11q22
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; CD40/CD40L signaling, organism-specific biosystem
• Function: metal ion binding; protein N-terminus binding; protein binding; transcription coactivator activity; ubiquitin-protein ligase activity; zinc ion binding