Recombinant Human BHLHE40, His-tagged

• Cat.No.: BHLHE40-10221H
• Product Overview: Recombinant Human BHLHE40 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-412a.a.
• Description: This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: BHLHE40 basic helix-loop-helix family, member e40 [ Homo sapiens ]
• Official Symbol: BHLHE40
• Synonyms: BHLHE40; basic helix-loop-helix family, member e40; basic helix loop helix domain containing, class B, 2 , BHLHB2, STRA13; class E basic helix-loop-helix protein 40; differentiated embryo chondrocyte expressed gene 1; bHLHe40; DEC1; differentially expressed in chondrocytes 1; class B basic helix-loop-helix protein 2; stimulated by retinoic acid gene 13 protein; enhancer-of-split and hairy-related protein 2; differentially expressed in chondrocytes protein 1; basic helix-loop-helix domain containing, class B, 2; HLHB2; BHLHB2; STRA13; Stra14; SHARP-2; FLJ99214
• Gene ID: 8553
• mRNA Refseq: NM_003670
• Protein Refseq: NP_003661
• MIM: 604256
• UniProt ID: O14503
• Chromosome Location: 3p26
• Pathway: BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; Circadian rhythm pathway, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem
• Function: DNA binding; E-box binding; MRF binding; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptio