Recombinant Human BAG5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BAG5-4749H
• Product Overview: BAG5 MS Standard C13 and N15-labeled recombinant protein (NP_001015048) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 56 kDa
• AA Sequence: MRFHWLPTLSEPFDRNQELETCIRP LWTPSGSACETEHNKSMDMGNQHPS ISRLQEIQKEVKSVEQQVIGFSGLS DDKNYKKLERILTKQLFEIDSVDTE GKGDIQQARKRAAQETERLLKELEQ NANHPHRIEIQNIFEEAQSLVREKI VPFYNGGNCVTDEFEEGIQDIILRL THVKTGGKISLRKARYHTLTKICAV QEIIEDCMKKQPSLPLSEDAHPSVA KINFVMCEVNKARGVLIALLMGVNN NETCRHLSCVLSGLIADLDALDVCG RTEIRNYRREVVEDINKLLKYLDLE EEADTTKAFDLRQNHSILKIEKVLK RMREIKNELLQAQNPSELYLSSKTE LQGLIGQLDEVSLEKNPCIREARRR AVIEVQTLITYIDLKEALEKRKLFA CEEHPSHKAVWNVLGNLSEIQGEVL SFDGNRTDKNYIRLEELLTKQLLAL DAVDPQGEEKCKAARKQAVRLAQNI LSYLDLKSDEWEYTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BAG5 BCL2-associated athanogene 5 [ Homo sapiens (human) ]
• Official Symbol: BAG5
• Synonyms: BAG5; BCL2-associated athanogene 5; BAG family molecular chaperone regulator 5; bcl-2-associated athanogene 5; BAG-family molecular chaperone regulator-5; BAG-5
• Gene ID: 9529
• mRNA Refseq: NM_001015048
• Protein Refseq: NP_001015048
• MIM: 603885
• UniProt ID: Q9UL15