Recombinant Human BAG1

• Cat.No.: BAG1-27434TH
• Product Overview: Recombinant full length Human Bag1 protein; 230 amino acids; predicted mwt: 26 kDa

Specification

• Description: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
• Source: E. coli
• Tissue specificity: Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tu
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Contains 1 BAG domain.Contains 1 ubiquitin-like domain.
• Tag: Non
• Full Length: Full L.

Gene Information

• Gene Name: BAG1 BCL2-associated athanogene [ Homo sapiens ]
• Official Symbol: BAG1
• Synonyms: BAG1; BCL2-associated athanogene; BAG family molecular chaperone regulator 1
• Gene ID: 573
• mRNA Refseq: NM_001172415
• Protein Refseq: NP_001165886
• MIM: 601497
• Uniprot ID: Q99933
• Chromosome Location: 9p12
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: chaperone binding; protein binding; receptor signaling protein activity