Recombinant Human B3GNT1, GST-tagged

• Cat.No.: B3GNT1-10102H
• Product Overview: Recombinant Human B3GNT1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 66-415a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 [ Homo sapiens ]
• Official Symbol: B3GNT1
• Synonyms: B3GNT1; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; B3GNT6, UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 6; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; B3GN T1; BETA3GNTI; iGAT; iGNT; iGnT; poly-N-acetyllactosamine extension enzyme; i-beta-1,3-N-acetylglucosaminyltransferase; beta-1,3-N-acetylglucosaminyltransferase bGnT-6; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6; B3GNT6; B3GN-T1
• Gene ID: 11041
• mRNA Refseq: NM_006876
• Protein Refseq: NP_006867
• MIM: 605517
• UniProt ID: O43505
• Chromosome Location: 11q13.2
• Pathway: Glycosaminoglycan biosynthesis - keratan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - keratan sulfate, conserved biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, organism-specific biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups