Recombinant Human AZIN1, His-tagged

• Cat.No.: AZIN1-3521H
• Product Overview: Antizyme inhibitor 1 (AZIN1)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 448
• Description: Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of AZIN1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: AZIN1 antizyme inhibitor 1 [ Homo sapiens ]
• Official Symbol: AZIN1
• Synonyms: AZIN1; antizyme inhibitor 1; OAZIN, ornithine decarboxylase antizyme inhibitor; OAZI; ODC1L; ornithine decarboxylase 1 like; AZI; ornithine decarboxylase antizyme inhibitor; OAZIN; MGC691; MGC3832
• Gene ID: 51582
• mRNA Refseq: NM_015878
• Protein Refseq: NP_056962
• MIM: 607909
• UniProt ID: O14977
• Chromosome Location: 8p22-q21.3
• Pathway: Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of ornithine decarboxylase (ODC), organism-specifi
• Function: enzyme inhibitor activity; ornithine decarboxylase activator activity; ornithine decarboxylase inhibitor activity