AZIN1
-
Official Full Name
antizyme inhibitor 1 -
Overview
Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene. -
Synonyms
AZIN1;antizyme inhibitor 1;OAZIN, ornithine decarboxylase antizyme inhibitor;OAZI;ODC1L;ornithine decarboxylase 1 like;AZI;Ornithine decarboxylase antizyme inhibitor;OTTHUMP00000227423;OTTHUMP00000227424;OAZIN
Recombinant Proteins
- Human
- Chicken
- Mouse
- Cynomolgus
- Rhesus macaque
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- E.Coli or Yeast
- Sf9 Insect Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Flag
- Non
- C-IgG1 Fc-Avi
- Myc&DDK
- His&Fc&Avi
Involved Pathway
AZIN1 involved in several pathways and played different roles in them. We selected most pathways AZIN1 participated on our site, such as Diurnally regulated genes with circadian orthologs,Metabolism,Metabolism of amino acids and derivatives, which may be useful for your reference. Also, other proteins which involved in the same pathway with AZIN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of amino acids and derivatives | PPM1K,SLC25A10,NQO1,CKMT2A,OAZ1,SLC25A21,PCBD1,HIBADHA,CKMB,CKMT1B |
| Regulation of ornithine decarboxylase (ODC) | OAZ1A,OAZ3,AZIN1B,OAZ2,OAZ2B,OAZ1,AZIN1A |
| Metabolism | CA13,PYGMB,CYP2B6,UCP2,AK7A,PPM1L,SLC5A2,LBR,CYP2AD6,ADH8A |
| Diurnally regulated genes with circadian orthologs | MYF6,KLF9,CRY1,SF3A3,STBD1,G0S2,GFRA1,CEBPB,ZFR,ERC2 |
| Metabolism of polyamines | CKMB,CKMT1B,OAZ1A,SLC6A12,PAOX,CKBA,AMD2,AZIN1A,SLC25A15,SLC6A8 |
Protein Function
AZIN1 has several biochemical functions, for example, ornithine decarboxylase activator activity,NOT ornithine decarboxylase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AZIN1 itself. We selected most functions AZIN1 had, and list some proteins which have the same functions with AZIN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT ornithine decarboxylase activity | AZIN1A,AZIN2,AZIN1B |
| protein binding | ATG12,PCDH17,PSMC6,KRT18,RCHY1,FTL,ALOX5,APBB1IP,SIK3,GAP43 |
| ornithine decarboxylase activator activity | AZIN1A,AZIN1B,AZIN2,PRLR |
Interacting Protein
AZIN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AZIN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AZIN1.
OAZ3;OAZ2;KHDRBS1;ADSSL1;ABCC2;OAZ1
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