Recombinant Human ATM protein, GST-tagged

• Cat.No.: ATM-185H
• Product Overview: Recombinant Human ATM(2667-end) fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~70 kDa
• Purity: >70%
• Applications: Western Blot
• Stability: 1 year at -70 centigrade from the date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05μg/μl
• Protein length: 2667-end a.a.

Gene Information

• Gene Name: ATM ataxia telangiectasia mutated [ Homo sapiens ]
• Official Symbol: ATM
• Synonyms: ATM; ataxia telangiectasia mutated; ATA, ataxia telangiectasia mutated (includes complementation groups A, C and D) , ATC, ATD, ATDC; serine-protein kinase ATM; TEL1; telomere maintenance 1; homolog (S. cerevisiae); TELO1; AT mutated; A-T mutated; TEL1, telomere maintenance 1, homolog; AT1; ATA; ATC; ATD; ATE; ATDC; MGC74674; DKFZp781A0353
• Gene ID: 472
• mRNA Refseq: NM_000051
• Protein Refseq: NP_000042
• MIM: 607585
• UniProt ID: Q13315
• Chromosome Location: 11q22-q23
• Function: 1-phosphatidylinositol-3-kinase activity; ATP binding; DNA binding; DNA-dependent protein kinase activity; histone serine kinase activity; nucleotide binding; protein N-terminus binding; protein binding; protein complex binding; protein dimerization activity; protein serine/threonine kinase activity