Recombinant Human ATG4C, GST-tagged
| Cat.No. : | ATG4C-9976H |
| Product Overview : | Recombinant Human ATG4C protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 1-300a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name | ATG4C ATG4 autophagy related 4 homolog C (S. cerevisiae) [ Homo sapiens ] |
| Official Symbol | ATG4C |
| Synonyms | ATG4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C (S. cerevisiae) , APG4C, AUT (S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase (S. cerevisiae) , AUTL1; cysteine protease ATG4C; AUTL3; FLJ14867; autophagin-3; APG4 autophagy 4 homolog C; AUT-like 3 cysteine endopeptidase; AUT-like 1, cysteine endopeptidase; autophagy-related protein 4 homolog C; autophagy-related cysteine endopeptidase 3; APG4C; AUTL1; APG4-C; |
| Gene ID | 84938 |
| mRNA Refseq | NM_032852 |
| Protein Refseq | NP_116241 |
| MIM | 611339 |
| UniProt ID | Q96DT6 |
| Chromosome Location | 1p31.3 |
| Pathway | Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; |
| Function | cysteine-type endopeptidase activity; peptidase activity; |
Not For Human Consumption!
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