Recombinant Human ATG4B Protein, His-tagged

• Cat.No.: ATG4B-003H
• Product Overview: Recombinant Human ATG4B protein (2-393) with a N-terminal histidine-tag was expressed in E. coli.

Specification

• Description: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 50 mM HEPES, pH 8.0, 150 mM sodium chloride, 10% glycerol
• Molecular Mass: 43.4 kDa
• Protein length: 2-393
• Purity: ≥80% estimated by SDS-PAGE
• Stability: ≥ 1 year
• Storage: Store at -80 centigrade
• Shipping: Dry ice in continental US; may vary elsewhere

Gene Information

• Gene Name: ATG4B autophagy related 4B cysteine peptidase [ Homo sapiens (human) ]
• Official Symbol: ATG4B
• Synonyms: ATG4B; autophagy related 4B cysteine peptidase; APG4B; AUTL1; cysteine protease ATG4B; APG4 autophagy 4 homolog B; ATG4 autophagy related 4 homolog B; AUT-like 1 cysteine endopeptidase; autophagin-1; autophagy-related cysteine; endopeptidase 1; autophagy-related protein 4 homolog B; hAPG4B
• Gene ID: 23192
• mRNA Refseq: NM_013325
• Protein Refseq: NP_037457
• MIM: 611338
• UniProt ID: Q9Y4P1