Recombinant Human ASIC4, GST-tagged

• Cat.No.: ASIC4-9282H
• Product Overview: Recombinant Human ASIC4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Antigen Description: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predom
• Description: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-350a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ASIC4 acid-sensing (proton-gated) ion channel family member 4 [ Homo sapiens (human) ]
• Official Symbol: ASIC4
• Synonyms: ASIC4; acid-sensing (proton-gated) ion channel family member 4; ACCN4; BNAC4; acid-sensing ion channel 4; amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; brain sodium channel 4; HGNC:21263; Ensembl:ENSG00000072182; HPRD:16231; MIM:606715; Vega:OTTHUMG00000058928
• Gene ID: 55515
• mRNA Refseq: NM_182847.2
• Protein Refseq: NP_878267.2
• MIM: 606715
• UniProt ID: Q96FT7
• Chromosome Location: 2q35
• Pathway: Ion channel transport, organism-specific biosystem; Stimuli-sensing channels, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
• Function: ion channel activity; sodium channel activity; sodium ion transmembrane transporter activity