Recombinant Human ASF1 Anti-Silencing Function 1 Homolog B (S. cerevisiae), His-tagged

• Cat.No.: ASF1B-6956H
• Product Overview: Recombinant human ASF1B protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 protein in yeast. This protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl, 1mM DTT.
• Molecular Mass: 23.4 kDa(210aa), confirmed by MALDI-TOF
• Protein length: 1-202aa
• AA Sequence: MAKVSVLNVA VLENPSPFHS PFRFEISFEC SEALADDLEW KIIYVGSAES EEFDQILDSV LVGPVPAGRH MFVFQADAPN PSLIPETDAV GVTVVLITCT YHGQEFIRVG YYVNNEYLNP ELRENPPMKP DFSQLQRNIL ASNPRVTRFH INWDNNMDRL EAIETQDPSL GCGLPLNCTP IKGLGLPGCI PGLLPENSMD CILEHHHHHH
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ASF1B ASF1 anti-silencing function 1 homolog B (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ASF1B
• Synonyms: ASF1B; ASF1 anti-silencing function 1 homolog B (S. cerevisiae); histone chaperone ASF1B; FLJ10604; hAsf1; hAsf1b; hCIA-II; CCG1-interacting factor A-II; anti-silencing function protein 1 homolog B; CIA-II
• Gene ID: 55723
• mRNA Refseq: NM_018154
• Protein Refseq: NP_060624
• MIM: 609190
• UniProt ID: Q9NVP2
• Chromosome Location: 19p13.12
• Function: histone binding