Recombinant Human ASB7 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ASB7-3244H
• Product Overview: ASB7 MS Standard C13 and N15-labeled recombinant protein (NP_078984) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
• Molecular Mass: 30.7 kDa
• AA Sequence: MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSMTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ASB7 ankyrin repeat and SOCS box containing 7 [ Homo sapiens (human) ]
• Official Symbol: ASB7
• Synonyms: ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; ASB-7; ankyrin repeat and SOCS box-containing 7; FLJ22551; FLJ25192
• Gene ID: 140460
• mRNA Refseq: NM_024708
• Protein Refseq: NP_078984
• MIM: 615052
• UniProt ID: Q9H672