Recombinant Human ARL1, His-tagged

• Cat.No.: ARL1-9847H
• Product Overview: Recombinant Human ARL1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-181a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ARL1 ADP-ribosylation factor-like 1 [ Homo sapiens ]
• Official Symbol: ARL1
• Synonyms: ARL1; ADP-ribosylation factor-like 1; ADP-ribosylation factor-like protein 1; ARFL1
• Gene ID: 400
• mRNA Refseq: NM_001177
• Protein Refseq: NP_001168
• MIM: 603425
• UniProt ID: P40616
• Chromosome Location: 12q23.3
• Function: GTP binding; GTPase activity; enzyme activator activity; metal ion binding; nucleotide binding; protein domain specific binding