ARL1
-
Official Full Name
ADP-ribosylation factor-like 1 -
Overview
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. [provided by RefSeq, Jul 2008] -
Synonyms
ARL1;ADP-ribosylation factor-like 1;ARFL1;ADP-ribosylation factor-like protein 1
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- Human
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
ARL1 involved in several pathways and played different roles in them. We selected most pathways ARL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ARL1 has several biochemical functions, for example, GTP binding,GTPase activity,enzyme activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL1 itself. We selected most functions ARL1 had, and list some proteins which have the same functions with ARL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein domain specific binding | KCTD13,PKD1,TJP1,SLC34A2,VCP,ARFIP1,HPCAL4,NLRP1,MTOR,HMGB2 |
| GTPase activity | ATL1,EEFSEC,GTPBP4,RAP2A,EEF1A1L2,RAB33A,RAB4A,RAB39A,TUBA1C,RAB22A |
| GTP binding | MMAA,NOA1,RAB1A,RAB9A,RAP2C,DNM1B,RAB33A,ARL13A,GBP4,RAB10 |
| metal ion binding | HPX,RFNG,PCGF5B,DDR1,BTK,TDO2,CYP2P8,ZNF524,ASAP2A,CNOT8 |
| enzyme activator activity | CLPS,TIMP2,DCP1B,DCP1A,MGST2,GTF3C4,MMP24,PPP1R12B,ALDH1A2,SFTPB |
Interacting Protein
ARL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL1.
GCC2;RIOK3;HLA-B;CDK5RAP3;C20orf24;BRF2;GSTK1;PHLDA3;q81z98_bacan;pi3p;PTBP3;MYC;MME;NEDD1
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