Recombinant Human ARHGAP8 Protein, His-tagged

• Cat.No.: ARHGAP8-2703H
• Product Overview: Recombinant Human ARHGAP8 protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Description: This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 53.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ARHGAP8 Rho GTPase activating protein 8 [ Homo sapiens ]
• Official Symbol: ARHGAP8
• Synonyms: BPGAP1; PP610
• Gene ID: 23779
• mRNA Refseq: NM_001017526.1
• Protein Refseq: NP_001017526