Recombinant Human ARHGAP24 Protein, His-tagged

• Cat.No.: ARHGAP24-2581H
• Product Overview: Recombinant Human ARHGAP24 protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 73.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ARHGAP24 Rho GTPase activating protein 24 [ Homo sapiens ]
• Official Symbol: ARHGAP24
• Synonyms: FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
• Gene ID: 83478
• mRNA Refseq: NM_001025616
• Protein Refseq: NP_001020787
• MIM: 610586
• UniProt ID: Q8N264