Recombinant Human AQP7 Protein, His-tagged

• Cat.No.: AQP7-238H
• Product Overview: Recombinant Human AQP7 Protein (Gly218-Phe342) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.4 kDa
  Accurate Molecular Mass: 17 kDa
• Protein length: Gly218-Phe342
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: AQP7 aquaporin 7 [ Homo sapiens (human) ]
• Official Symbol: AQP7
• Synonyms: AQP7; aquaporin 7; AQP7L; aquaporin-7; AQP9; AQPap; AQP-7; aquaporin adipose; aquaglyceroporin-7; GLYCQTL; MGC149555; MGC149556
• Gene ID: 364
• mRNA Refseq: NM_001170
• Protein Refseq: NP_001161
• MIM: 602974
• UniProt ID: O14520