Recombinant Human AQP4, GST-tagged

• Cat.No.: AQP4-9782H
• Product Overview: Recombinant Human AQP4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 208-323a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AQP4 aquaporin 4 [ Homo sapiens ]
• Official Symbol: AQP4
• Synonyms: AQP4; aquaporin 4; aquaporin-4; MIWC; WCH4; aquaporin type4; mercurial-insensitive water channel; HMIWC2; MGC22454
• Gene ID: 361
• mRNA Refseq: NM_001650
• Protein Refseq: NP_001641
• MIM: 600308
• UniProt ID: P55087
• Chromosome Location: 18q11.2-q12.1
• Pathway: Aquaporin-mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Passive Transport by Aquaporins, organism-specific biosystem; Regulation of Water Balance by Renal Aquaporins, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Vasopressin-regulated water reabsorption, organism-specific biosystem
• Function: transporter activity; water channel activity; water transmembrane transporter activity