Recombinant Human APPL1 Protein, MYC/DDK-tagged

• Cat.No.: APPL1-16H
• Product Overview: Recombinant Human APPL1 protein was expressed in HEK293 cells with C-terminal MYC/DDK tag.

Specification

• Description: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 79.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 [ Homo sapiens ]
• Official Symbol: APPL1
• Synonyms: APPL1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; APPL; DIP13alpha; AKT2 interactor; signaling adaptor protein DIP13alpha; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; DCC-interacting protein 13-alpha;Dip13-alpha; DIP13A; KIAA1428;Dip13-alpha
• Gene ID: 26060
• mRNA Refseq: NM_012096
• Protein Refseq: NP_036228
• MIM: 604299
• UniProt ID: Q9UKG1