Recombinant Human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative), His-tagged

• Cat.No.: APOBEC4-309H
• Product Overview: APOBEC4, 1-367aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-367 a.a.
• Description: The APOBEC4 is a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in Mrna editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. Recombinant human APOBEC4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 44.0kDa (390aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTE FCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRH IILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSG SHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSG QLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) [ Homo sapiens ]
• Official Symbol: APOBEC4
• Synonyms: APOBEC4; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative); C1orf169, chromosome 1 open reading frame 169; putative C->U-editing enzyme APOBEC-4; FLJ25691; MGC26594; RP1 127C7.4; putative C->U-editing enzyme APOBEC-4; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4; C1orf169
• Gene ID: 403314
• mRNA Refseq: NM_203454
• Protein Refseq: NP_982279
• MIM: 609908
• UniProt ID: Q8WW27
• Chromosome Location: 1q25.3
• Function: hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; metal ion binding; zinc ion binding