Recombinant Human APOBEC3H, His-tagged

• Cat.No.: APOBEC3H-9758H
• Product Overview: Recombinant Human APOBEC3H protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-182a.a.
• Description: This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H [ Homo sapiens ]
• Official Symbol: APOBEC3H
• Synonyms: APOBEC3H; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H; DNA dC->dU-editing enzyme APOBEC-3H; ARP10; DNA dC-> dU-editing enzyme APOBEC-3H; ARP-10; APOBEC-related protein 10; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H
• Gene ID: 164668
• mRNA Refseq: NM_001166002
• Protein Refseq: NP_001159474
• MIM: 610976
• UniProt ID: Q6NTF7
• Chromosome Location: 22q13.1
• Function: cytidine deaminase activity; hydrolase activity; metal ion binding; zinc ion binding