Recombinant Human APOA1, GST-tagged
Cat.No. : | APOA1-9747H |
Product Overview : | Recombinant Human APOA1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | March 29, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | 19-267a.a. |
Description : | This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | APOA1 apolipoprotein A-I [ Homo sapiens ] |
Official Symbol | APOA1 |
Synonyms | APOA1; apolipoprotein A-I; apo-AI; apoA-I; MGC117399; |
Gene ID | 335 |
mRNA Refseq | NM_000039 |
Protein Refseq | NP_000030 |
MIM | 107680 |
UniProt ID | P02647 |
Chromosome Location | 11q23-q24 |
Pathway | ABC-family proteins mediated transport, organism-specific biosystem; ABCA transporters in lipid homeostasis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Amyloids, organism-specific biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; Disease, organism-specific biosystem; |
Function | apolipoprotein A-I receptor binding; apolipoprotein receptor binding; beta-amyloid binding; cholesterol binding; contributes_to cholesterol transporter activity; cholesterol transporter activity; enzyme binding; high-density lipoprotein particle binding; |
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◆ Native Proteins | ||
APOA1-26121TH | Native Human APOA1, Protein A-tagged | +Inquiry |
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APOA1-256H | Native Human APOA1 protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
APOA1-3088HCL | Recombinant Human APOA1 cell lysate | +Inquiry |
APOA1-1497MCL | Recombinant Mouse APOA1 cell lysate | +Inquiry |
Not For Human Consumption!
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