Recombinant Human APCDD1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: APCDD1-4325H
• Product Overview: APCDD1 MS Standard C13 and N15-labeled recombinant protein (NP_694545) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 58.8 kDa
• AA Sequence: MSWPRRLLLRYLFPALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGSNRCTNPTYTLIIRGKIRLRQASWIIRGGTEADYQLHNVQVICHTEAVAEKLGQQVNRTCPGFLADGGPWVQDVAYDLWREENGCECTKAVNFAMHELQLIRVEKQYLHHNLDHLVEELFLGDIHTDATQRMFYRPSSYQPPLQNAKNHDHACIACRIIYRSDEHHPPILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFSIYARGRYSRGVLSSRVMGGTEFVFKVNHMKVTPMDAATASLLNVFNGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHTEYEIFKMEQDARGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEDLAEDSGSSLYGRAPGRHTWSLLLAALACLVPLLHWNIRRTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: APCDD1 adenomatosis polyposis coli down-regulated 1 [ Homo sapiens (human) ]
• Official Symbol: APCDD1
• Synonyms: APCDD1; adenomatosis polyposis coli down-regulated 1; protein APCDD1; B7323; hypoptrichosis simplex; adenomatosis polyposis coli down-regulated 1 protein; HHS; HTS; DRAPC1; FP7019
• Gene ID: 147495
• mRNA Refseq: NM_153000
• Protein Refseq: NP_694545
• MIM: 607479
• UniProt ID: Q8J025