Recombinant Human AP4S1 Protein, His-tagged

• Cat.No.: AP4S1-328H
• Product Overview: Recombinant Human AP4S1, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
• Source: E. coli
• Tag: His
• Form: 50mM Tris, 8M Urea, pH8.0.
• Molecular Mass: 18.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: AP4S1 adaptor-related protein complex 4, sigma 1 subunit [ Homo sapiens ]
• Official Symbol: AP4S1
• Synonyms: AP47B; CLA20; CPSQ6; SPG52; CLAPS4; AP4S1
• Gene ID: 11154
• mRNA Refseq: NM_001128126.2
• Protein Refseq: NP_001121598.1
• MIM: 607243
• UniProt ID: Q9Y587