Recombinant Human AP3B2 protein, His-tagged

• Cat.No.: AP3B2-920H
• Product Overview: Recombinant Human AP3B2 protein (Gly838-Gln1082), fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy.
• Source: E.coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 30 kDa
• Protein length: 245
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: AP3B2
• Official Symbol: AP3B2
• Synonyms: NAPTB; EIEE48
• Gene ID: 8120
• mRNA Refseq: NM_001278512.2
• Protein Refseq: NP_001265441.1
• MIM: 602166
• UniProt ID: Q13367