Recombinant Human AP1G1, GST-tagged

• Cat.No.: AP1G1-9708H
• Product Overview: Recombinant Human AP1G1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-350a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AP1G1 adaptor-related protein complex 1, gamma 1 subunit [ Homo sapiens ]
• Official Symbol: AP1G1
• Synonyms: AP1G1; adaptor-related protein complex 1, gamma 1 subunit; ADTG, CLAPG1; AP-1 complex subunit gamma-1; gamma1 adaptin; gamma adaptin; gamma1-adaptin; golgi adaptor HA1/AP1 adaptin gamma subunit; adaptor protein complex AP-1 subunit gamma-1; golgi adaptor HA1/AP1 adaptin subunit gamma-1; adapter-related protein complex 1 subunit gamma-1; clathrin assembly protein complex 1 gamma large chain; clathrin assembly protein complex 1 gamma-1 large chain; clathrin-associated/assembly/adaptor protein, large, gamma 1; ADTG; CLAPG1; MGC18255
• Gene ID: 164
• mRNA Refseq: NM_001030007
• Protein Refseq: NP_001025178
• MIM: 603533
• UniProt ID: O43747
• Chromosome Location: 16q23
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Disease, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; HIV Infection, organism-specific biosystem; Host Interactions of HIV factors, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: kinesin binding; protein binding; protein transporter activity; transporter activity