Recombinant Human Annexin A2, His-tagged

• Cat.No.: ANXA2-5278H
• Product Overview: Recombinant humanANXA2 contains 361 amino acids including a 6xHis Tag. Its molecular weight is41300 Dalton.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: ANXA2 also known as annexin II is a protein thatin humans is encoded by the ANXA2 gene. ANXA2 isinvolved in diverse cellular processes such as cell motility (especially thatof the epithelial cells), linkage of membrane-associated protein complexes tothe actin cytoskeleton, endocytosis, fibrinolysis, ion channel formation, andcell matrix interactions. It is a calcium-dependent phospholipid-bindingprotein whose function is to help organize exocytosis of intracellularproteins to the extracellular domain. Annexin II is a pleiotropic proteinmeaning that its function is dependent on place and time in the body.
• Form: Liquid in 20 mMTris-HCl + 0.5 M NaCl + 100 mM imidazole + 1 mM 2-mercaptoethanol, pH 8.0without preservative.
• Molecular Weight: 41.3 kDa
• Concentration: 0.5 mg/ml
• Applications: Western Blot;ELISA; Antibody Production; Protein Array
• Storage: Stable for 1 year inworking aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: ANXA2

Gene Information

• Gene Name: ANXA2 annexin A2 [ Homosapiens ]
• Synonyms: ANXA2; annexin A2;P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; annexin-2; protein I;annexin II; lipocortin II; chromobindin 8; chromobindin-8;OTTHUMP00000163650; calpactin I heavy chain; calpactin-1 heavy chain;calpactin I heavy polypeptide; placental anticoagulant protein IV; annexinA2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain;Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; Protein I;p36
• Gene ID: 302
• mRNA Refseq: NM_001002857
• Protein Refseq: NP_001002857
• MIM: 151740
• UniProt ID: P07355
• Chromosome Location: 15q22.2
• Pathway: ProstaglandinSynthesis and Regulation
• Function: Rab GTPase binding;calcium ion binding; calcium-dependent phospholipid binding; cytoskeletalprotein binding; phosphatidylinositol-4,5-bisphosphate binding; phospholipaseinhibitor activity; protein binding