Recombinant Human ANGPTL3, FLAG-tagged

• Cat.No.: ANGPTL3-397H
• Product Overview: Recombinant Human ANGPTL3(aa 1-222), fused at the C-terminus to a FLAG-tag, was expressed in HEK 293 cells.

Specification

• Description: This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
• Source: HEK293 cells
• Species: Human
• Tag: FLAG
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Molecular Mass: ~25kDa (SDS-PAGE)
• Endotoxin: <0.1EU/μg purified protein (LAL test; Lonza).
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°CLong Term Storage: -20°CHandling Advice: After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 0.5 mg/ml
• Protein length: 1-222 a.a.

Gene Information

• Gene Name: ANGPTL3 angiopoietin-like 3 [ Homo sapiens (human) ]
• Official Symbol: ANGPTL3
• Synonyms: ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin 5; angiopoietin-related protein 3; Angiopoietin-5; ANG-5; UNQ153/PRO179; OTTHUMP00000010719
• Gene ID: 27329
• mRNA Refseq: NM_014495
• Protein Refseq: NP_055310
• MIM: 604774
• UniProt ID: Q9Y5C1
• Chromosome Location: 1p31.3
• Function: enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity