Recombinant Human AMPD1 protein, MYC/DDK-tagged

• Cat.No.: AMPD1-8877H
• Product Overview: Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Specification

• Source: HEK293T
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 90 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -20 centigrade. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: AMPD1 adenosine monophosphate deaminase 1 [ Homo sapiens ]
• Official Symbol: AMPD1
• Synonyms: MAD; MADA; MMDD; AMPD; AMP deaminase 1; AMPD isoform M; skeletal muscle AMPD
• Gene ID: 270
• mRNA Refseq: NM_000036
• Protein Refseq: NP_000027
• UniProt ID: P23109