Recombinant Human Aminoacylase 1, T7-tagged
Cat.No. : | ACY1-27H |
Product Overview : | Recombinant Human Aminoacylase-1 produced inE.Coliis a non-glycosylated, polypeptide chain containing amino acids 1-408 and having a total molecular mass of 46.9 kda. ACY-1 contains T7 tag at N-terminus. ACY1 is purified by proprietary chromatographic techniques. |
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Species : | Human |
Source : | E.coli |
Tag : | T7 |
Protein Length : | 1-408 a.a. |
Description : | Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes. |
Physical Appearance : | Sterile Filtered clear solution. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Formulation : | Aminoacylase-1 at a concentration of 0.1 mg/ml in 10 mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3. |
Applications : | • ELISA • MS • Inhibition Assays • Western Blotting. |
Stability : | ACYLASE although stable at 14°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name | ACY1 aminoacylase 1 [ Homo sapiens ] |
Synonyms | ACY1; aminoacylase 1; ACY1D; ACYLASE; aminoacylase-1;N-acyl-L-amino-acid amidohydrolase; ACY-1; EC 3.5.1.14; N-acyl-L-amino-acid amidohydrolase |
Gene ID | 95 |
mRNA Refseq | NM_000666 |
Protein Refseq | NP_000657 |
UniProt ID | Q03154 |
Chromosome Location | 3p21.1 |
MIM | 104620 |
Pathway | Arginine and proline metabolism; Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid; Metabolic pathways |
Function | aminoacylase activity; hydrolase activity; metal ion binding; metal ion binding; metallopeptidase activity; protein dimerization activity; zinc ion binding |
◆ Recombinant Proteins | ||
ACY1-242H | Recombinant Human ACY1 protein(Met1-Ser408), His-tagged | +Inquiry |
ACY1-27198TH | Recombinant Human ACY1, His-tagged | +Inquiry |
ACY1-1152H | Recombinant Human ACY1 Protein, DDK-tagged | +Inquiry |
ACY1-27H | Recombinant Human Aminoacylase 1, T7-tagged | +Inquiry |
ACY1-487H | Recombinant Human ACY1 Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ACY1-725HCL | Recombinant Human ACY1 cell lysate | +Inquiry |
ACY1-3095MCL | Recombinant Mouse ACY1 cell lysate | +Inquiry |
Not For Human Consumption!
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