Recombinant Human AMFR, GST-tagged

Description :	This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
Source :	E. Coli or Yeast
Species :	Human
Tag :	GST
Form :	This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length :	643
Purity :	>90%
Notes :	Small volumes of AMFR recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage :	Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer :	PBS pH 7.4, 50% glycerol
Warning :	This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Name	AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol	AMFR
Synonyms	AMFR; autocrine motility factor receptor, E3 ubiquitin protein ligase; autocrine motility factor receptor; gp78; RNF45; RING finger protein 45; GP78;
Gene ID	267
mRNA Refseq	NM_001144
Protein Refseq	NP_001135
MIM	603243
UniProt ID	P26442
Chromosome Location	16q21
Pathway	Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;
Function	ligase activity; metal ion binding; protein binding; receptor activity; receptor activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding;

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