Recombinant Human ALOX12B, GST-tagged

• Cat.No.: ALOX12B-9590H
• Product Overview: Recombinant Human ALOX12B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 352-701a.a.
• Description: This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ALOX12B arachidonate 12-lipoxygenase, 12R type [ Homo sapiens ]
• Official Symbol: ALOX12B
• Synonyms: ALOX12B; arachidonate 12-lipoxygenase, 12R type; arachidonate 12-lipoxygenase, 12R-type; 12R LOX; 12R-lipoxygenase; epidermis-type lipoxygenase 12; 12R-LOX
• Gene ID: 242
• mRNA Refseq: NM_001139
• Protein Refseq: NP_001130
• MIM: 603741
• UniProt ID: O75342
• Chromosome Location: 17p13.1
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; IL23-mediated signaling events, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem
• Function: arachidonate 12-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity