Recombinant Human ALOX12B, GST-tagged
| Cat.No. : | ALOX12B-9590H |
| Product Overview : | Recombinant Human ALOX12B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 352-701a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name | ALOX12B arachidonate 12-lipoxygenase, 12R type [ Homo sapiens ] |
| Official Symbol | ALOX12B |
| Synonyms | ALOX12B; arachidonate 12-lipoxygenase, 12R type; arachidonate 12-lipoxygenase, 12R-type; 12R LOX; 12R-lipoxygenase; epidermis-type lipoxygenase 12; 12R-LOX; |
| Gene ID | 242 |
| mRNA Refseq | NM_001139 |
| Protein Refseq | NP_001130 |
| MIM | 603741 |
| UniProt ID | O75342 |
| Chromosome Location | 17p13.1 |
| Pathway | Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; IL23-mediated signaling events, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Serotonergic synapse, organism-specific biosystem; |
| Function | arachidonate 12-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity; |
Not For Human Consumption!
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