ALOX12B
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Official Full Name
arachidonate 12-lipoxygenase, 12R type -
Synonyms
ALOX12B;arachidonate 12-lipoxygenase, 12R type;arachidonate 12-lipoxygenase, 12R-type;12R LOX;12R-lipoxygenase;epidermis-type lipoxygenase 12;12R-LOX
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
ALOX12B involved in several pathways and played different roles in them. We selected most pathways ALOX12B participated on our site, such as Arachidonic acid metabolism,Metabolic pathways,Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALOX12B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arachidonic acid metabolism | CBR1,CYP2P9,CYP4F18,HPGDS,PLA2G12A,PTGR1,CYP1A1,CYP2C37,PTGIS,PLA2G4A |
| Metabolic pathways | GUK1B,PRDX6,GK,ACSL4A,TK2,LTA4H,PAFAH1B1B,XYLB,SDS,AGPS |
| Serotonergic synapse | PRKCB,ARAF,GNAI3,PRKCA,MAPK3,BRAF,CYP2D26,GNB1,KCND2,PRKACA |
Protein Function
ALOX12B has several biochemical functions, for example, arachidonate 12-lipoxygenase activity,iron ion binding,linoleate 9S-lipoxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALOX12B itself. We selected most functions ALOX12B had, and list some proteins which have the same functions with ALOX12B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron ion binding | CYP2W1,KDM3A,JHDM1D,CYP4A14,CYP2K6,CYP2Y3,EGLN3,P4HA3,CYP4A11,CYP2K16 |
| arachidonate 12-lipoxygenase activity | ALOX12,ALOX12E,ALOX15 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | P4HA1A,P4HA2,ALOX8,P4HA3,BCO2,ALOX12E,ALOX5B.3,ALOX12,ADOB,P4HA1B |
| protein binding | IL1RAPL1,IGFLR1,GZMB,CCDC101,PELP1,EFHC2,MAVS,KANSL2,FGD2,GFPT2 |
Interacting Protein
ALOX12B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALOX12B here. Most of them are supplied by our site. Hope this information will be useful for your research of ALOX12B.
ALOXE3;TGM1
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