Recombinant Human ALKBH3, GST-tagged
Cat.No. : | ALKBH3-9584H |
Product Overview : | Recombinant Human ALKBH3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | March 31, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | GST |
Protein Length : | C-term-139a.a. |
Description : | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]). |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name | ALKBH3 alkB, alkylation repair homolog 3 (E. coli) [ Homo sapiens ] |
Official Symbol | ALKBH3 |
Synonyms | ALKBH3; alkB, alkylation repair homolog 3 (E. coli); alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC 1; prostate cancer antigen 1; prostate cancer antigen-1; alkylated DNA repair protein alkB homolog 3; ABH3; PCA1; DEPC1; DEPC-1; FLJ43614; MGC118790; MGC118792; MGC118793; |
Gene ID | 221120 |
mRNA Refseq | NM_139178 |
Protein Refseq | NP_631917 |
MIM | 610603 |
UniProt ID | Q96Q83 |
Chromosome Location | 11p11.2 |
Pathway | ABH3 mediated Reversal of Alkylation Damage, organism-specific biosystem; DNA Damage Reversal, organism-specific biosystem; DNA Repair, organism-specific biosystem; Reversal of Alkylation Damage By DNA Dioxygenases, organism-specific biosystem; |
Function | DNA-N1-methyladenine dioxygenase activity; L-ascorbic acid binding; cytosine C-5 DNA demethylase activity; ferrous iron binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular o |
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ALKBH3-9584H | Recombinant Human ALKBH3, GST-tagged | +Inquiry |
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Not For Human Consumption!
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